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Overview
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UbcH10 (Ubc2C) is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It plays a major role in the mitosis in cell cycle by binding to the anaphase-promoting complex/cyclosome (APC/C), which causes autoubiquitination and degradation of UbcH10. This in turn stabilizes cyclin A, promoting cells enter into S phase. UbcH10 also promotes ubiquitination of many substrates of APC/C.
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- Properties
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Overview
Coomassie-stained SDS-PAGE Lane 1: Molecular weight markers Lane 2: 5 µg purified 6xHis-Ube2C (UbcH10 )
6xHis-Ube2C (UbcH10 )
6xHis-Ube2C (UbcH10 )
Catalog Number:
EUCE097607UBP
Mfr. No.:
C1301
Price:
$416
Size:
100 µg
Quantity:
Add to Cart: