6xHis-Ube2C (UbcH10 )

6xHis-Ube2C (UbcH10 )

Catalog Number:
EUCE097607UBP
Mfr. No.:
C1301
Price:
$416
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • UbcH10 (Ubc2C) is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It plays a major role in the mitosis in cell cycle by binding to the anaphase-promoting complex/cyclosome (APC/C), which causes autoubiquitination and degradation of UbcH10. This in turn stabilizes cyclin A, promoting cells enter into S phase. UbcH10 also promotes ubiquitination of many substrates of APC/C.

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      • Properties
        • Protein Name
          UBCH10; dJ447F3.2
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          19.7 kDa
          Sequence
          NCBI RefSeq: NM_007019

          * Research Use Only

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