6xHis-Ube2B

6xHis-Ube2B

Catalog Number:
EUCE097609UBP
Mfr. No.:
C1201
Price:
$416
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • Ube2B is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 95% amino acid sequence identity with Ube2A. One function of Ube2B involves the formation of Ube2B/ Rad18 (an E3 enzyme) complex to monoubiquitinate proliferating cell nuclear antigen (PCNA) thus activating it to repair DNA damage. The Ube2B/Rad18 complex is recruited to the replication fork of the damaged DNA to start the post-replication repair.

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      • Properties
        • Protein Name
          HR6B; UBC2; HHR6B; RAD6B; E2-17kDa
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          17.3 kDa
          Sequence
          NCBI RefSeq: NM_003337

          * Research Use Only

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