Name: 1-(3,4-Dichlorophenyl)-3-(1,3-thiazol-2-yl)thiourea
Price: 496.00 USD

- Overview
  - 1-(3,4-Dichlorophenyl)-3-(1,3-thiazol-2-yl)thiourea is a thiourea derivative synthesized from 1,3-thiazole. The 1,3-thiazoles are an important group of compounds due to their wide range of applications in biopharma. The thioureas have been described as the most useful class of agents, with a large number of activities including antiviral, antibacterial, and lipoprotein (HDL)-elevating properties. The compound is active against Gram-positive cocci and Mycobacteria. It has been found to inhibit biofilm formation in wild type and methicillin-resistant strains of Staphylococcus epidermidis.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    The electron-withdrawing halogen atom, especially at the 3rd position of the phenyl group is significantly important for the antimicrobial activity.
- Properties
  - Molecular Formula
    
    C10H7CL2N3S2
    
    Molecular Weight
    
    304.2
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: 1-(3,4-Dichlorophenyl)-3-(1,3-thiazol-2-yl)thiourea is active against Gram-positive cocci including Staphylococcus species including methicillin-resistant S. epidermidis. It is also effective for Mycobacteria, including M. tuberculosis. It also has cytotoxicity and antiviral activity on a large set of DNA and RNA viruses, including HIV type 1 (HIV-1).
    
    Microbiology Applications: 1-(3,4-Dichlorophenyl)-3-(1,3-thiazol-2-yl)thiourea has in vitro tuberculostatic activity against M. tuberculosis. The compound also has an inhibitory effect for biofilm formation by standard and selected hospital methicillin-resistant strains of S. epidermidis (MRSE).