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ZXH-3-26

ZXH-3-26

Catalog Number:
PTC1441538INV
Mfr. No.:
V3577
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      • Overview

        • ZXH-3-26 is a novel, potent and selective degrader of BRD4 with a DC50/5h (half-maximal degradation after 5 hours of treatment) of ~ 5 nM. Heterobifunctional small-molecule degraders that induce protein degradation through ligase-mediated ubiquitination have shown considerable promise as a new pharmacological modality.

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      • Properties
        • Categories
          PROTACs
          CAS Number
          2243076-67-5
          Molecular Formula
          C38H37CLN8O7S
          Molecular Weight
          785.27
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C(NCCCCCCNC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)S3)C(C7=CC=C(Cl)C=C7)=N1

          * For research use only

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