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Overview
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Background
TG2 is present in various tissues and involved in a plentitude of physiological as well as pathological processes. The enzyme catalyses the acyl transfer reaction between the γ-carboxyamide group of peptidebound glutamine residues and a variety of primary amines, particularly the ε-amino group of lysine (Lorand L. et al., 1962). This assay enables the measurement of TG2 activity according to the chromogenic hydroxamate detection principle (Grossowicz, N. et al., 1950).
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- Properties
- Applications
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Overview