WaTx

WaTx

Catalog Number:
P004516950LIF
Mfr. No.:
PEPTIDE-PN-120
Price:
Inquiry
  • Size:
    1mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Stabilizes the transient receptor potential cation channel 1 (TRPA1) in an active state.
          WaTx, also known as wasabi receptor toxin, is the active component of the venom of the Australian black rock scorpion Urodacus manicatus. WaTx targets the mechanical and chemical stress sensor transient receptor potential cation channel 1 (TRPA1), which it stabilizes in an active state characterized by prolonged channel openings and low Ca2+ permeability. WaTx elicits acute pain and pain hypersensitivity, but fails to trigger efferent release of neuropeptides and neurogenic inflammation typically produced by other toxins. WaTx is a unique pharmacological probe for dissecting TRPA1 function and its contribution to acute and persistent pain.

          Please contact us for availability.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Peptides
          Alternative Name
          Wasabi receptor toxin
          Molecular Formula
          C164H245N45O53S5
          Molecular Weight
          3855.3
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in DMSO as stock.
          Other Properties
          Sequence: H-Ala-Ser-Pro-Gln-Gln-Ala-Lys-Tyr-Cys-Tyr-Glu-Gln-Cys-Asn-Val-Asn-Lys-Val-Pro-Phe-Asp-Gln-Cys-Tyr-Gln-Met-Cys-Ser-Pro-Leu-Glu-Arg-Ser-OH (disulphide bridge between C9 and C27 and C13 and C23),ASPQQAKYCYEQCNVNKVPFDQCYQMCSPLERS
          Modification: Disulphide bridges between cysteine 9 and cysteine 27 and cysteine 13 and cysteine 23
          Storage
          Storage desiccated, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

    We Also Recommend

    WKYMVM

    WKYMVM

    $375

    WKYMVm

    WKYMVm

    $375