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Overview
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Selective FPRL1 and FPRL2 receptor agonist.
WKYMVM is a potent N-formyl peptide receptor agonist. WKYMVM activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. WKYMVM also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and can activate NADPH oxidase.
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Overview