Name: Virginiamycin
Price: 416.00 USD

- Overview
  - Virginiamycin is a streptogramin, and a mixture of Virginiamycin M1 and Virginiamycin S1. The commercial mixture is 75% Virginiamycin M1 and 25 % Virginiamycin S1, along with less abundant S analogs. The two components of the mixture have differing solubilities, which can affect the binding to the 50S ribosome, which in turn influences the bacteriostatic effects. Virginiamycin is soluble in DMSO and DMF.
    
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    Background
    
    Virginiamycin inhibits protein synthesis, targeting to the 50S ribosome and inducing a conformational change at the peptidyl transferase center. Protein synthesis is inhibited in both actively growing and static bacterial cells.
- Properties
  - CAS Number
    
    11006-76-1
    
    Molecular Formula
    
    C28H35N3O7 (for M1), C43H49N7O10 (for S1)
    
    Molecular Weight
    
    525.6 (for M1); 823.9 (for S1)
    
    Appearance
    
    White solid
    
    Solubility
    
    DMSO, DMF
    
    Other Properties
    
    Source: Streptomyces virginiae
    Purity Level: >99% by HPLC (75% Virginamycin M1, 20% Virginiamycin S1, 5% Other minor analogues)
    
    Storage
    
    -20°C
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Gram-positive bacteria, such as Lactobacillus spp.
    
    Microbiology Applications: Virginiamycin is used in bioproduction, specifically to reduce contaminating bacteria when fermenting yeast for bioethanol production.