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Overview
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Virginiamycin is a streptogramin, and a mixture of Virginiamycin M1 and Virginiamycin S1. The commercial mixture is 75 % Virginiamycin M1 and 25 % Virginiamycin S1, along with less abundant S analogs. The mixture can be used to reduce contaminating bacteria during yeast fermentation for bioethanol production. Virginiamycin is soluble in DMSO and DMF.
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Background
Virginiamycin inhibits protein synthesis, targeting the 50S ribosome and inducing a conformational change at the peptidyl transferase center. Protein synthesis is inhibited in both actively growing and static bacterial cells.
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- Properties
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Overview