Trace Amine Associated Receptor 8 - ExpressMAX™ Human GPCR ORF Clones

Trace Amine Associated Receptor 8 - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268703CAN
Mfr. No.:
G0631-B; G0631-Plus
Price:
$581
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      • Overview
        • The discovery of a family of GPCRs, some of which bind and are activated by biogenic trace amines, has prompted speculation as to the physiological role of these receptors. Observations associated with the distribution of these trace amine associated receptors (TAARs) suggest that it may be involved in depression, attention-deficit hyperactivity disorder, eating disorders, migraine headaches and Parkinson’s disease. Preliminary in vitro data, obtained using cloned receptors, also suggest a role for TAARs in the function of hallucinogens.

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Human GPCR ORF Clones
          Other Properties
          Plasmid size: 7002 pb
          Promoter: PEF1α
          ORF Sequence (GenBank based): NM_053278
          Protein Sequence (SwissProt): Q969N4
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: TA5, TAR5, TRAR5 or TaR-5
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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