Chemokine (C-X-C motif) Receptor 7 - ExpressMAX™ Human GPCR ORF Clones

Chemokine (C-X-C motif) Receptor 7 - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268706CAN
Mfr. No.:
G0541-B; G0541-Plus
Price:
$573
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      • Overview
        • CXCR7 is encoded in Humans by the CXCR7 gene. It is a member of the GPCR family and was considered as an orphan receptor, its endogenous ligand had not been identified. It is classified as a chemokine receptor able to bind the chemokines CXCL12/SDF-1 and CXCL11. Ligand binding to CXCR7 activates MAP kinases through Beta-arrestins and thus has functions primarily by sequestering the chemokine CXCL12. It is also a coreceptor for Human immunodeficiency viruses (HIV).

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Human GPCR ORF Clones
          Other Properties
          Plasmid size: 6427 bp
          Promoter: pMLV
          ORF Sequence (GenBank based): NM_020311.2
          Protein Sequence (SwissProt): P25106
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: RDC1, ACKR3, RDC-1 or CMKOR1
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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