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Overview
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Background
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
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Overview
TNF Receptor II Rabbit mAb
TNF Receptor II Rabbit mAb
Catalog Number:
A001550729RED
Mfr. No.:
RDSA67326
Price:
$470
Size:
100μL
Quantity:
Add to Cart: