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Overview
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Background
The ADAM10 prodomain acts as a chaperone that stabilizes mature ADAM protein folding, and prevents target-protein shedding through inhibition of ADAM10 proteinase activity. Mature ADAM10 is the major α-secretase responsible for cleavage of Notch, APP, cadherins, and prion protein. The ADAM10 protein cleaves receptor tyrosine kinases and their associated ligands and displays a wide range of regulatory functions across related signaling pathways.
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- Properties
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Overview
ADAM10 Rabbit mAb
ADAM10 Rabbit mAb
Catalog Number:
A001550730RED
Mfr. No.:
RDSA67327
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.