Name: Tertiapin Q
Price: 331.00 USD

- Overview
  - Inward rectifier K+ ?channel blocker.
    Tertiapin-Q is a high affinity blocker of inward-rectifier K+ channels. Tertiapin-Q is a stable derivative of the bee venom toxin tertiapin where the methionine residue at position 13 has been replaced with glutamine, which is far less susceptible to oxidation by air. Tertiapin-Q and native tertiapin have very similar pharmacologucal properties. Tertiapin-Q also binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are 1.3 and 13.3 nM respectively) and shows selectivity over Kir2.1 channels.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    TPNQ, TPN(Q)
    
    Molecular Formula
    
    C106H175N35O24S4
    
    Molecular Weight
    
    2452
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble to 2 mg/ml in water
    
    Other Properties
    
    Sequence: H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2: disulphide bridges between Cys-3 and Cys-14 and Cys-5 and Cys-18,ALCNCNRIIIPHQCWKKCGKK-NH2
    Modification: Disulphide bridges between C-3 and C14 and C-5 and C-18, Lys-21 is a C-terminal amide
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

We Also Recommend

TFLLR-NH2

$523

TFLLR-NH2

$211

TIP

$257

TIP 39

$397