Name: Tat-βsyn-degron
Price: 381.00 USD

- Overview
  - β-Synuclein knockdown peptide.
    Tat-βsyn-degron is a blood-brain barrier and plasma membrane permeable β-synuclein knockdown peptide which can reduce the level of
    β-synuclein by proteasomal degradation. Tat-βsyn-degron decreases β-synuclein aggregates and microglial activation in an β-synuclein preformed fibril model of spreading synucleinopathy in transgenic mice overexpressing human A53T β-synuclein, and reduces β-synuclein levels and significantly decreases the neuronal damage and motor impairment in a mouse toxicity model of Parkinsons disease.
    
    Please contact us for availability.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Cell Penetrating Peptides
    
    Alternative Name
    
    Tat-βsyn-degron peptide
    
    Molecular Formula
    
    C132H237N59O31
    
    Molecular Weight
    
    3146.71
    
    Appearance
    
    Freeze fried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in water
    
    Other Properties
    
    Sequence: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Thr-Lys-Ser-Gly-Val-Tyr-Leu-Val-Gly-Arg-Arg-Arg-Gly-OH,YGRKKRRQRRRRTKSGVYLVGRRRG
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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