T-VDA epi

Catalog Number:
TVDA089648VEN
Mfr. No.:
T-VDAepi
Price:
  • Size:
    12 species, 2D HPLC, 1mg protein/fraction
    Quantity:
    Add to Cart:
      • Overview
        • Covalent modifications of DNA (e.g. cytosine methylation) or of histone proteins (e.g. lysine acetylation, lysine and arginine methylation, serine and threonine phosphorylation, and lysine ubiquitination and sumoylation) play central roles in many types of epigenetic regulation. Epigenetic factors that produce these modifications can be affected by development (in utero, childhood), environmental chemicals, drug/pharmaceuticals, ageing and diet which in turn can lead to cancer, autoimmune diseases, neurodegenerative disorders and diabetes. Given the large number of epigenetic factors, identifying small molecules and biologics with satisfactory selectivity profiles presents a huge challenge for epigenetic target drug discovery.

          • Venoms are supplied lyophilised in Echo qualified acoustic source plates (Labcyte Inc) and are useable on any SBS footprint liquid handling device or by hand.
          • 384-well format has 200ng venom fraction per well, suggested dilution 20µl as hit fractions are typically active at 5µg/ml and below.
          • 1536-well format also available.

          Please contact us at  for specific academic pricing.

      • Properties
        • Storage
          Recommend storage at -20°C upon receipt. Lyophilised T-VDAs™ are shipped at ambient temperature, as they are stable for several weeks.
          Research Field
          Epigenetics – KDM and Bromodomains
      • Applications
        • Application Description
           T-VDAs™ can be used in any biochemical or cell based assay like any other compound array. The fractionated T-VDAs perform well in Phenotypic assays.
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