SP6 RNA Polymerase (20 U/μL)

SP6 Bacteriophage RNA Polymerase is a DNA-dependent RNA polymerase that exhibits high specificity for the SP6 bacteriophage promoter. It catalyzes the incorporation of NTPs downstream of the SP6 promoter on single- or double-stranded DNA templates, synthesizing RNA complementary to the DNA template downstream of the SP6 promoter. This enzyme not only performs conventional RNA synthesis but also recognizes modified NTPs, such as biotin-, digoxigenin-, or fluorescein-labeled NTPs, making it suitable for a wide range of research applications and biotechnological uses.

Features
• High Purity: Free from exonuclease, endonuclease, non-specific nuclease, and RNase contamination, ensuring clean and reliable transcription.
• High Transcription Efficiency: Delivers robust in vitro RNA synthesis performance comparable to leading international brands.
• Recombinant Source: Produced in recombinant E. coli expressing the Salmonella typhimurium SP6 RNA polymerase gene.
• Defined Promoter Recognition: Recognizes the SP6 promoter sequence (5′-ATTTAGGTGACACTATAGAAGNG-3′) for precise and efficient transcription initiation.

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