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Overview
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Sinefungin is a nucleoside S-adenosyl-1-methionine analog. Potent, competitive methyltransferase (protein, DNA, and RNA methyltransferases) inhibitor. Binds with greater affinity to the adenine-specific DNA methyltransferase M.Taql than S-adenosyl-L-homocysteine. Inhibits biofilm formation by Streptococcus pneumoniae.
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