RNase Inhibitor, GMP Grade (40U/μl)

- Overview
  - RNase Inhibitor inhibits RNase A, B and C with high efficiency by forming a 1:1 complex with them. The characteristics of RNase Inhibitor are similar to those derived from pig liver and human placenta. The inhibition is reversible, as the complex can be dissociated by urea and sulfhydryl reagents in which RNase refolds and the inhibitor is inactivated. It can be directly added to the reaction containing RNA. Different from other competitive inhibitors (e.g., nucleic acids, inorganic phosphoric acids), this product is a protein, which can be easily removed from the reaction by phenol extraction. However, the reverse transcriptase RNase H could not be inhibited.
    Recombinant RNase Inhibitor is GMP Grade produced in E. coli. Our manufacturing processes are strictly controlled to ensure the end products free from host protein or nucleic acid contaminations and other impurities following the Pharmaceutical Manufacturing Guidelines. We guarantee the manufacturing and quality control comply with GMP regulation for tracking each and every step of the manufacturing process, including raw material sourcing.
    This product has completed the DMF record of FDA and passed the HALAL certification.
    
    Please contact us at for specific academic pricing.
    
    More Details
    
    FDA DMF Filed Enzymes
- Properties
  - Storage
    
    At -20±5 °C.
    
    Expression system
    
    E. coli
    
    Endotoxin
    
    ＜5EU/ml
    
    Activity
    
    39KU/ml-41KU/ml (Activity Definition: One unit is defined as the amount of Inhibitor required to inhibit the activity of 5ng of RNase A by 50%. Activity is measured by the inhibition of hydrolysis of cytidine 2', 3'-cyclic monophosphate by RNase A.)
    
    * For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.
- Reference
  - Cascade-Responsive “Oxidative Stress Amplifiers” Simultaneously Destroy Lysosomes and Co-Deliver CRISPR/Cas9 to Enhance Oxidative Damage in Tumor
    Ultrasensitive SARS-CoV-2 diagnosis by CRISPR-based screen-printed carbon electrode
    Rapid and Sensitive Diagnosis of Drug-Resistant FLT3-F691L Mutation by CRISPR Detection

Datasheet

RNase Inhibitor, GMP Grade (40U/μl)

RNase Inhibitor, GMP Grade (40U/μl)

More Details

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