Riociguat

Riociguat

Catalog Number:
FC01364898APE
Mfr. No.:
APE-A3767
Price:
$244
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      • Overview
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          Background

          Riociguat (BAY 63-2521; BAY 632521) is a novel drug that is currently in clinical development by Bayer. Riociguat (BAY 63-2521; BAY 632521) is a stimulator of soluble guanylate cyclase (sGC). At the moment Phase III clinical trials investigate the use of riociguat as a new approach to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of a novel class of sGC stimulators.

      • Properties
        • Categories
          Soluble guanylate cyclase (sGC) stimulator
          Alternative Name
          BAY 63-2521; BAY 632521; methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate
          CAS Number
          625115-55-1
          Molecular Formula
          C20H19FN8O2
          Molecular Weight
          422.42
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          insoluble in EtOH; insoluble in H2O; ≥16.95 mg/mL in DMSO
          Storage
          Store at -20°C
          SMILES
          CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC

          * For Research Use Only

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