Name: RG33
Price: 381.00 USD

- Overview
  - Apolipoprotein A1 (ApoA-I) mimetic, improves glucose clearance and control.
    RG33 is a peptide corresponding to the two last helical segments, amino acid residues 209-241 of apolipoprotein A1 (ApoA-I), the major protein component of high-density lipoprotein (HDL) particles in plasma. ApoA-I has a specific role in lipid metabolism and enables efflux of molecules by accepting fats from within cells for transport and metabolism elsewhere. In vivo RG33 peptide efficiently solubilizes lipid vesicles, and promotes the efflux of cholesterol from cultured macrophages. In vitro RG33 peptide significantly improves the glucose clearance capacity of insulin resistant mice and provides systemic glucose control in an insulin resistant mouse model.
    
    Please contact us for availability.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Peptides
    
    Molecular Formula
    
    C175H282N42O51
    
    Molecular Weight
    
    3790.41
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    >3 mg/ml in water
    
    Other Properties
    
    Sequence: Ac-Pro-Ala-Leu-Glu-Asp-Leu-Arg-Gln-Gly-Leu-Leu-Pro-Val-Leu-Glu-Ser-Phe-Lys-Val-Ser-Phe-Leu-Ser-Ala-Leu-Glu-Glu-Tyr-Thr-Lys-Lys-Leu-Asn-NH2,Ac-PALEDLRQGLLPVLESFKVSFLSALEEYTKKLN-NH2
    Modification: N terminal acetyl, C terminal amide
    
    Storage
    
    Store desiccated, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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