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Recombinant Human Suppressor Of IKBKE 1

Recombinant Human Suppressor Of IKBKE 1

Catalog Number:
P001414068ABE
Mfr. No.:
Abe32-4845
Price:
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  • Size:
    10 µg
    Quantity:
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      • Overview

        • SIKE1 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 230 amino acids (1-207 a.a) andhaving a molecular mass of 26.1kDa. SIKE1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Suppressor ofIKBKE 1 also known as SIKE1 belongs to the SIKE family. SIKE interacts withIKK-epsilon and TBK1 and function as a suppressor of TLR3 and virus-triggeredinterferon activation pathways. In addition, SIKE1 perform by disrupting the interactions of IKBKE or TBK1 withTICAM1/TRIF, IRF3 andDDX58/RIG-I. SIKE1 does not inhibit NF-kappa-B activationpathways.

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      • Properties
        • Protein Name
          Suppressor Of IKBKE 1, SIKE, Suppressor Of IKK Epsilon, SuppressorOf IKK-Epsilon.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greaterthan 85% as determined by SDS-PAGE.
          Formulation
          SIKE1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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