Name: Recombinant Human Signal-Regulatory Protein Alpha
Price: Inquiry

- Overview
  - SIRPA Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 370 amino acids (27-373 a.a) andhaving a molecular mass of 40.4kDa. SIRPA is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Signal-Regulatory Protein Alpha, SIRPA belongs to thesignal-regulatory-protein (SIRP) family, as well as the immunoglobulin super family. The membersof the SIRP family are receptor-type transmembrane glycoproteins which are involved in the negative regulation of receptor tyrosinekinase-coupled signaling processes. SIRPA can be phosphorylatedby tyrosine kinases. The phospho-tyrosine residues of this PTP have been shownto recruit SH2 domaincontaining tyrosine phosphatases (PTP), and perform as substrates of PTPs. SIRPA take part in signal transduction mediated by a varietyof growth factor receptors. CD47 has been shown to be a ligand for SIRPA.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Signal-Regulatory Protein Alpha, SHPS1, CD172Antigen-Like Family Member A, Inhibitory Receptor SHPS-1, Macrophage FusionReceptor, PTPNS1, SIRP, P84, BIT, MFR, Brain-Immunoglobulin-Like Molecule With Tyrosine-BasedActivation Motifs, Brain Ig-Like
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    SIRPA protein solution (0.5mg/ml) containing PBS buffer (pH 7.4), 10% glycerol and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Signal-Regulatory Protein Alpha

Recombinant Human Signal-Regulatory Protein Alpha

We Also Recommend

Recombinant Human Signal-Regulatory Protein Gamma

Recombinant Human Sirtuin-5

Recombinant Human Sirtuin-6