Name: Recombinant Human Sirtuin-5
Price: Inquiry

- Overview
  - SIRT5 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain topological domain containing 300 aminoacids (34-310 a.a) and having a molecular mass of 32.5kDa. SIRT5 is fused to a 23amino acid His-tag at N-terminus & purified by proprietary chromatographictechniques. SIRT5 belongs to the Sirtuin family of proteins, homologs to the yeast Sir2 protein. Sirtuin family members hold a sirtuin core domain and grouped into four classes. The protein encoded by this gene is included in class III of the sirtuin family. Human sirtuins functions were not yet determined; still, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies propose that human sirtuin could operate as intracellular regulatory protein with mono-ADP-ribosyltransferase activity.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Sirtuin 5, NAD-Dependent Lysine Demalonylase AndDesuccinylase Sirtuin-5, Mitochondria, NAD-Dependent Protein Deacylase Sirtuin-5Mitochondrial, Silent Mating Type Information Regulation 2 (S.Cerevisiae)Homolog 5, NAD-Dependent Deacetylase Sirtuin-5
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    SIRT5 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 1mM DTT and 30% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Sirtuin-5

Recombinant Human Sirtuin-5

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