Name: Recombinant Human SH3-domain GRB2-like endophilin B2
Price: Inquiry

- Overview
  - SH3GLB2 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 418 amino acids (1-395a.a.) and having a molecular mass of 46.4 kDa. SH3GLB2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Endophilin-B2 (SH3GLB2) belongs to the endophilin B subgroup. The endophilins comprise a family of proteins that relates with amphiphysin, synaptojanin and dynamin and are involved in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are coherent with their cellular functions at the neuronal synapse. SH3GLB2 is ubiquitously expressed however presents highest levels in brain, adult lung, ovary, and spinal cord. Low levels of SH3GLB2 are found in Down syndrome and reflect brain dysgenesis.
    
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- Properties
  - Protein Name
    
    PP6569, PP9455, Endophilin-B2, KIAA1848, SH3 domain-containing GRB2-like protein B2.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    SH3GLB2 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human SH3-domain GRB2-like endophilin B2

Recombinant Human SH3-domain GRB2-like endophilin B2

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