Recombinant Human Serum Albumin (OsrHSA) Cell Culture Grade

Human serum albumin (HSA) is an important supplement in cell culture medium. Thanks to HSA ability to carry and to deliver important nutrients to cells, it increase the viscosity of the medium, provide a mechanical protection for cells. Moreover, HSA binds toxins thus avoiding toxic effects, binds excessive proteins acting as a buffer.
In recent years, there has been an increased demand for animal-free components to replace serum or animal originated supplements to eliminate the risk of viruses and mycoplasma contaminants. Using the rice endosperm specific expression platform, the recombinant human serum albumin (OsrHSA), which is animal component free, can provide an economical and safe approach for the production of non–animal-derived compounds, which will facilitate development of products from cell cultures.

Human plasma is also in limited supply. Rice as bioreactor show great promise as a flexible system for the production and processing of OsrHSA with intact biochemical features on a large scale. The rice endosperm specific expression platform is easy to be large-scale, because the rice endosperm has the protein body, which can keeps proteins stability and bioactivity. At present, the production capacity of OsrHSA is almost 1000 kg/year.

We also offer different types of customized OsrHSA to satisfy different requirement, including:
• Low sodium octanoate OsrHSA
• High sodium octanoate OsrHSA
• Excipient grade OsrHSA lyophilized powder
• Charcoal-stripped Fatty acids free OsrHSA

Please contact us at for specific academic pricing.

Background

OryzHiExp - A Rice Endosperm Specific Expression Platform
OryzHiExp platform uses rice endosperm cells to express various recombinant proteins and small peptides at high levels. Through this platform, innovative animal-free protein products with a wide range of applications can be produced, such as OsrHSA, OsrhTF, OsrhFN, and other recombinant growth factors.
ADVANTAGES
• Elimination of the potential risk of viral and other unknown contaminants
• Avoid the quality changes from different batches, improve the repeatability of cellculture and experiment results
• Regulatory compliant with well-defined components
• Stable supply and manufacture capability at large scales to meet bulk processing needs
• Simplify the downstream bio-processing or biological research