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Overview
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Human epidermal growth factor, also known as EGF, is a 6kD protein with 53 amino acid residues and three intramolecular disulfide bonds. By binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface, EGF results in a variety of biochemical changes within the cell, rising intracellular calcium levels, increasing glycolysis, protein synthesis and regulating the gene expression, including the gene for EGFR that ultimately lead to DNA synthesis and cell proliferation.
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Background
OryzHiExp - A Rice Endosperm Specific Expression Platform
OryzHiExp platform uses rice endosperm cells to express various recombinant proteins and small peptides at high levels. Through this platform, innovative animal-free protein products with a wide range of applications can be produced, such as OsrHSA, OsrhTF, OsrhFN, and other recombinant growth factors.
ADVANTAGES
• Elimination of the potential risk of viral and other unknown contaminants
• Avoid the quality changes from different batches, improve the repeatability of cellculture and experiment results
• Regulatory compliant with well-defined components
• Stable supply and manufacture capability at large scales to meet bulk processing needs
• Simplify the downstream bio-processing or biological research
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