Name: Recombinant Human Parkinson Disease Protein 2
Price: Inquiry

- Overview
  - PARK2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 485 amino acids (1-465) and having a molecular mass of 53.8 kDa. PARK2 is fused to a 20 amino acid His-tag at N-terminus. PARK2 is an element in a multiprotein E3 ubiquitin ligase complex which mediates the targeting of substrate proteins for proteasomal degradation. PARK2 alterations can result in Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing creates multiple transcript variants encoding distinct isoforms.
    
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- Properties
  - Protein Name
    
    Parkin RBR E3 Ubiquitin Protein Ligase, Parkinson Juvenile Disease Protein 2, Parkinson Protein 2 E3 Ubiquitin Protein Ligase (Parkin), Parkinson Disease (Autosomal Recessive, Juvenile) 2 Parkin, PRKN, AR-JP, PDJ, E3 Ubiquitin Ligase, LPRS2, EC 6.3.2
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 80% as determined by SDS-PAGE.
    
    Formulation
    
    The PARK2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Parkinson Disease Protein 2

Recombinant Human Parkinson Disease Protein 2

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