Name: Recombinant Human Par-6 Partitioning Defective 6 Homolog Beta
Price: Inquiry

- Overview
  - PARD6B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 395 amino acids (1-372) and having a molecular mass of 43.6kDa. PARD6B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Partitioning defective 6 homolog beta (PARD6B) belongs to the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Cellular asymmetry is crucial for the development of multicellular organisms. PARD (partitioning-defective) proteins have central roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. PARD6B is expressed in pancreas and in both the adult and the fetal kidney, and is weakly expressed in the placenta and the lung.
    
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- Properties
  - Protein Name
    
    Partitioning defective 6 homolog beta, PAR-6 beta, PAR-6B, PARD6B, PAR6B.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    The PARD6B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea, 20% glycerol and 0.2M NaCl.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Par-6 Partitioning Defective 6 Homolog Beta

Recombinant Human Par-6 Partitioning Defective 6 Homolog Beta

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