Recombinant Human Keratinocyte Growth Factor (OsrhKGF)

Recombinant Human Keratinocyte Growth Factor (OsrhKGF)

Catalog Number:
P001410027HEA
Mfr. No.:
HYC027M01
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      • Overview
        • Keratinocyte growth factor (KGF), also known as FGF-7, is a member of FGF family. It is a cytokine discovered in the culture supernatant of embryonic lung fibroblasts. KGF, an effective epithelial cell-specific growth factor, is secreted by mesenchymal cells and its receptor is distributed in epithelial cells. Its mitotic activity is mainly manifested in keratinocytes, which can specifically stimulate the proliferation, migration and differentiation of epithelial cells. It also closely relate to organ development, wound healing, tumorigenesis and immune reconstruction etc.
          OsrhKGF, expressed in the rice endosperm platform and purified by chromatography, is animal component free and has high biological activity. The rice endosperm platform makes the manufacture capability at hundreds of gram scales to meet your bulk bioprocessing needs.

          Please contact us at for specific academic pricing.

          Background

          OryzHiExp - A Rice Endosperm Specific Expression Platform
          OryzHiExp platform uses rice endosperm cells to express various recombinant proteins and small peptides at high levels. Through this platform, innovative animal-free protein products with a wide range of applications can be produced, such as OsrHSA, OsrhTF, OsrhFN, and other recombinant growth factors.
          ADVANTAGES
          • Elimination of the potential risk of viral and other unknown contaminants
          • Avoid the quality changes from different batches, improve the repeatability of cellculture and experiment results
          • Regulatory compliant with well-defined components
          • Stable supply and manufacture capability at large scales to meet bulk processing needs
          • Simplify the downstream bio-processing or biological research

      • Properties
        • Source
          Oryza sativa (rice)
          Type
          Recombinant Proteins
          Purification
          More than 95% as determined by SDS-PAGE.
          Formulation
          It is lyophilized with trehalose and histidine as the stabilizers.
          Storage
          Stored at temperatures -20°C for at least 12 months. It is recommended to reconstitute the lyophilized OsrhKGF in sterile water. Use as soon as possible after opening. Please avoid freeze-thaw cycles.
          Endotoxin
          Less than 0.1 EU/mg
          Activity
          The ED50 is ≤1ng/ml determined by a cell proliferation assay using MCF-7, corresponding to a specific activity of ≥1×10⁵ Units/mg.

          * For research, laboratory and manufacture use only. Not intended for direct use on humans.

      • Applications
        • Application Description
          Mammalian cell culture; Cosmetic and beauty care

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