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Overview
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Lysozyme (LYZ) is a small protein with 14.7 kDa molecular weight, contains 130 amino acid. Lysozyme is a potent antimicrobial enzyme, by catalytic hydrolysis of their cell wall peptidoglycan, which contains sugars and amino acids. The sugar component consists of A-(1, 4)-linked N-acetylglucosamine and N-acetylmuramic acid and this bond is broken by lysozyme. This compromises the bacterial cell wall and causes the bacterium to burst under the high internal osmotic pressure. The recombinant human lysozyme (OsrhLYZ) was expressed in the patented rice endosperm, has been demonstrated that has the same physical and chemical with the native lysozyme.
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Background
OryzHiExp - A Rice Endosperm Specific Expression Platform
OryzHiExp platform uses rice endosperm cells to express various recombinant proteins and small peptides at high levels. Through this platform, innovative animal-free protein products with a wide range of applications can be produced, such as OsrHSA, OsrhTF, OsrhFN, and other recombinant growth factors.
ADVANTAGES
• Elimination of the potential risk of viral and other unknown contaminants
• Avoid the quality changes from different batches, improve the repeatability of cellculture and experiment results
• Regulatory compliant with well-defined components
• Stable supply and manufacture capability at large scales to meet bulk processing needs
• Simplify the downstream bio-processing or biological research
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Overview