Recombinant Human JAK2 (N-GST tag)

Recombinant Human JAK2 (N-GST tag)

Catalog Number:
E001278374APP
Mfr. No.:
Z500186
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • JAK2 is a member of intracellular non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. JAK2 has two near-identical phosphate-transferring domains. One domain exhibits the kinase activity while the other stabilizes the JAK conformational structure. JAK2 is the predominant JAK kinase activated in response to several growth factors and cytokines such as IL-3, GM-CSF and erythropoietin. JAK2 has been found to be constitutively associated with the prolactin receptor and is required for responses to gamma interferon.

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      • Properties
        • Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          63.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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