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Overview
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The protein has a predicted molecular mass of 27.7 kDa after removal of the signal peptide. The apparent molecular mass of IgG1-Fc is approximately 30-40 kDa due to glycosylation. IGHG1 (Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)) is a Protein Coding gene. Diseases associated with IGHG1 include Leukemia, Chronic Lymphocytic and Heavy Chain Deposition Disease. Among its related pathways are Interleukin-4 and 13 signaling and IL4-mediated signaling events. Gene Ontology (GO) annotations related to this gene include antigen binding. An important paralog of this gene is IGHG3.
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Overview