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Recombinant Human CDC42BPG (DMPK2) (N-GST tag)

Recombinant Human CDC42BPG (DMPK2) (N-GST tag)

Catalog Number:

E001278261APP

Mfr. No.:

Z500061

Price:

$672

Size:

10 µg

Quantity:

Add to Cart:

- Overview
  - Serine/threonine-protein kinase MRCK?, encoded by CDC42BPG gene, acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.
    
    Please contact us at for specific academic pricing.
- Properties
  - Name
    
    DMPK2; HSMDPKIN; KAPPA-200; MRCKG; MRCKgamma
    
    Source
    
    Insect cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
    
    Storage
    
    Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    
    Molecular Weight
    
    78.0 kDa
    
    Class
    
    Active Kinases
    
    * For research use only. Not for diagnostic or therapeutic use.

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