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Recombinant Human ALK (N-GST tag)

Recombinant Human ALK (N-GST tag)

Catalog Number:
E001278264APP
Mfr. No.:
Z500008
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • ALK or anaplastic lymphoma kinase is a receptor tyrosine kinase that was originally identified as a member of the insulin receptor subfamily that acquires transforming capability when truncated and fused to NPM (nucleophosmin) in the t(2;5) chromosomal rearrangement associated with ALCL Many chromosomal rearrangements leading to enhanced ALK activity have been described and are implicated in a number of cancer types. In the nervous system, ALK in the presence of ligand appears essential for axonal guidance, whereas in the absence of ligand, ALK expression can lead to developmental neuronal apoptosis.

          Please contact us at for specific academic pricing.

      • Properties
        • Name
          ALK (Ki-1), CD246, NBLST3, TFG/ALK
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          90.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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