Login / Register
0

Recombinant Human ALK1 (N-GST tag)

Recombinant Human ALK1 (N-GST tag)

Catalog Number:
E001278263APP
Mfr. No.:
Z500009
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • ALK1 is a serine/threonine-protein kinase receptor R3 precursor that mediates signal by TGFβ superfamily. ALK1 functions as a TGFβ type I receptor in endothelial cells and is responsible for human hereditary hemorrhagic telangiectasia (HHT) type II. Distinct Smad proteins (i.e., Smad2/Smad3 and Smad1/Smad5) show interaction with ALK1 and mediate TGFβ signaling. Northern blot and RT-PCR analysis show that ALK1 specifically induces expression of Smad6, Smad7, Id1, Id2, endoglin, STAT1, and interleukin 1 receptor in endothelial cells. ALK1 expression in inflammatory myofibroblastic tumor of the urinary bladder have also has been reported.

          Please contact us at for specific academic pricing.

      • Properties
        • Name
          ACVRL1, ACVRLK1, ALK1, HHT, HHT2, ORW2, SKR3, ALK1, TSR-I
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          64.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

    We Also Recommend

    Recombinant Human AKT2 (N-His tag)

    Recombinant Human AKT2 (N-His tag)

    $672

    Recombinant Human AKT3 (N-GST tag)

    Recombinant Human AKT3 (N-GST tag)

    $672

    Recombinant Human ALK (N-GST tag)

    Recombinant Human ALK (N-GST tag)

    $672

    Note: If you don't receive our verification email, do the following:

    Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.