Rebeccamycin

- Overview
  - Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. Rebeccamycin displays selective antitumor activity against several cell lines. Analogues of rebeccamycin have been tested in clinical trials for cancer therapy.
    
    Rebeccamycin is soluble in DMF and DMSO and is moderately soluble in methanol or ethanol.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Rebeccamycin's primary mechanism of action is via strong DNA intercalation resulting in the potent catalytic inhibition of both topoisomerases I and II.
- Properties
  - CAS Number
    
    93908-02-2
    
    Molecular Formula
    
    C27H21Cl2N3O7
    
    Molecular Weight
    
    570.4
    
    Appearance
    
    Dull yellow lyophilisate
    
    Storage
    
    -20°C
    
    * For research use only