Rat RANTES (CCL5)

Rat RANTES (CCL5)

Catalog Number:
P001418147ABE
Mfr. No.:
Abe32-12293
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      • Overview
        • Predicted MW: Monomer, 7.9 kDa (68 aa). Regulated upon activation, normal T cell expressed and secreted (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28. RANTES functions to recruit immune cells to inflammatory sites.

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      • Properties
        • Protein Name
          C-C motif chemokine
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
          Activity
          Biological Activity was determined byTHP-1 chemotaxis at <=250 ng/mL. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

          More Information

          UniProt
          Gene ID
          20304

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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