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Overview
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Predicted MW: Monomer, 8.9 kDa (83 aa). Resistin-like molecule-beta (RELM-beta ) is a member of the RELM family of secreted proteins containing conserved C-terminus cysteines. The RELM family consists of Resistin (FIZZ3), RELM-alpha (FIZZ1), RELM-beta (FIZZ2), and RELM-gamma (FIZZ4). Resistin and RELM-beta are the only RELM family members found in humans, whereas all four RELM family members are present in rodents. RELM-beta functions to increase fibroblast proliferation and differentiation, resulting in airway remodelling and increased inflammation.
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Overview