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Raltitrexed

Raltitrexed

Catalog Number:

L002370032APE

Mfr. No.:

APE-B1476

Price:

$180

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- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Raltitrexed (Tomudex, TDX, ZD 1694) is an antimetabolite drug used in cancer chemotherapy. It is an inhibitor of thymidylate synthase.
- Properties
  - Alternative Name
    
    (2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid
    
    CAS Number
    
    112887-68-0
    
    Molecular Formula
    
    C21H22N4O6S
    
    Molecular Weight
    
    458.49
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; ≥154 mg/mL in DMSO; ≥10.62 mg/mL in EtOH with ultrasonic
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC1=NC(=O)C2=C(N1)C=CC(=C2)CN(C)C3=CC=C(S3)C(=O)NC(CCC(=O)O)C(=O)O
    
    * For Research Use Only
- Reference
  - 1. Vincent Desrosiers, Corinne Barat, et al. "Thymidylate synthase is essential for efficient HIV-1 replication in macrophages." Virology. 2021 Sep;561:47-57. PMID:34146963

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