Raltitrexed

Raltitrexed

Catalog Number:
L002370032APE
Mfr. No.:
APE-B1476
Price:
$180
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      • Overview
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          Background

          Raltitrexed (Tomudex, TDX, ZD 1694) is an antimetabolite drug used in cancer chemotherapy. It is an inhibitor of thymidylate synthase.

      • Properties
        • Alternative Name
          (2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid
          CAS Number
          112887-68-0
          Molecular Formula
          C21H22N4O6S
          Molecular Weight
          458.49
          Purity
          98.00%
          Solubility
          insoluble in H2O; ≥154 mg/mL in DMSO; ≥10.62 mg/mL in EtOH with ultrasonic
          Storage
          Store at -20°C

          * For Research Use Only

      • Reference
        • 1. Vincent Desrosiers, Corinne Barat, et al. "Thymidylate synthase is essential for efficient HIV-1 replication in macrophages." Virology. 2021 Sep;561:47-57. PMID:34146963

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