PSB 1114

PSB 1114

Catalog Number:
L002372544APE
Mfr. No.:
APE-B7649
Price:
$744
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          PSB 1114 is a potent and selective agonist of P2Y2 receptor with EC50 value of 0.134 μM [1]. P2Y2 receptor is a purinergic G protein-coupled receptor and is activated by ATP and UTP. P2Y2 receptor is a potential target for treatment of cystic fibrosis. PSB 1114 is a potent and selective P2Y2 receptor agonist. PSB 1114 activated P2Y2, P2Y4 and P2Y6 with EC50 values of 0.134, 9.3 and 7.0 μM respectively and exhibited >60-fold selectivity versus P2Y6 and P2Y4 receptors [1].

      • Properties
        • Categories
          P2Y2 receptor agonist
          Molecular Formula
          C10H11F2N2Na4O13P3S
          Molecular Weight
          622.14
          Appearance
          Colourless liquid
          Purity
          98.00%
          Solubility
          <10mM in H2O
          Storage
          Store at -20°C
          SMILES
          FC(P([O-])([O-])=O)(P([O-])(OP([O-])(OC[[email protected]](O1)([H])[[email protected]](O)([H])[[email protected]](O)([H])C1([H])N2C=CC(S)=NC2=O)=O)=O)F.[Na+].[Na+].[Na+].[Na+]

          * For Research Use Only

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