PhenoDrive Synthetic Biomaterials

- Overview
  - PhenoDrive allows you to control the phenotype of your cells as in their natural microenvironment
    
    PhenoDrive has been successfully used in both single and co-cultures of a range of cells. Each PhenoDrive product has been specifically designed to either mimic a separate component of the extra cellular matrix essential for appropriate cell phenotype and function, or to manipulate the cells surrounding milieu to provide an environment that mimics that seen in vivo.
    
    The unique, bespoke design of each PhenoDrive allows the presentation of its bio-cue to the cells to ensure maximum effect.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    PhenoDrive are a family of synthetic, peptide-based products specifically designed to promote the appropriate in-vitro cell response to meet the needs of your research.
    PhenoDrives are an easy to use, one step addition to your current in-vitro 2D and 3D culture procedures that, as it is non gel-based, will not interfere with your microscopy or other methods of analysis. PhenoDrives can also be used as an additive for bioinks for 3D cell plotting applications that utilise cells of a neuronal origin.
    
    More Details
    
    PhenoDrive Biomimetic Substrates
- Properties
  - Storage
    
    PhenoDrives are supplied as a lyophilised powder for easy reconstitution in a range of aqueous or polar solvents. The lyophilised powder can be stored for up to 24 months at -20°C. Reconstituted PhenoDrives can be stored at -20°C and used within 3 months of freezing.
    
    * For research use only. Not for clinical use or for implantation in humans or animals.
- Applications
  - Application Description
    
    PhenoDrives are recommended for use as a coating for plastics in traditional 2D culture or the decoration of 3D scaffolds and incorporation into bioinks to promote the expansion, differentiation. And control of cells of mammalian origin.
- Reference
  - Perugini, V., Flaherty, S. M., & Santin, M. (2022). Development of scaffold-free vascularized pancreatic beta-islets in vitro models by the anchoring of cell lines to a bioligand-functionalized gelatine substrate. Journal of materials science. Materials in medicine, 33(4), 37. Perugini, V., & Santin, M. (2021). A Substrate-Mimicking Basement Membrane Drives the Organization of Human Mesenchymal Stromal Cells and Endothelial Cells Into Perivascular Niche-Like Structures. Frontiers in cell and developmental biology, 9, 701842. Perugini, V., & Santin, M. (2020). A comparative in vitro study of the effect of biospecific integrin recognition processes and substrate nanostructure on stem cell 3D spheroid formation. Journal of materials science. Materials in medicine, 31(4), 37.

Documents

Product Selection Guide

Application Note

PhenoDrive Synthetic Biomaterials

PhenoDrive Synthetic Biomaterials

Background

More Details

Documents

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