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PAMP 12 (human, porcine)

PAMP 12 (human, porcine)

Catalog Number:
P004516888LIF
Mfr. No.:
PEPTIDE-MG-010
Price:
$257
  • Size:
    1mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Endogenous MRGPRX2 agonist.
          PAMP 12 (human, porcine) corresponds to amino acids 9 to 20 of proadrenomedullin and is an endogenous peptide agonist of Mas related GPR X2 (MRGPRX2) with an EC50 of 57.2 nM. PAMP 12 (human, porcine) can cause hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. PAMP 12 (human, porcine) displays potent antimicrobial activity against standard bacterial strains, with a mechanism of action not involving the microbial cell membrane but instead targeting binding to bacterial DNA.

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          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Peptides
          Alternative Name
          PAMP (9-20)
          Molecular Formula
          C77H119N25O14
          Molecular Weight
          1618.95
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 1 mg/ml in water
          Other Properties
          Sequence: H-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2,FRKKWNKWALSR-NH2
          Modification: C-terminal amide
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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