PAMP 20 (human)

PAMP 20 (human)

Catalog Number:
P004516889LIF
Mfr. No.:
PEPTIDE-MG-020
Price:
$298
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • Endogenous MRGPRX2 agonist.
          PAMP 20 (human) is an endogenous peptide agonist of Mas related GPR X2 (MRGPRX2) with an EC50 of 251 nM. PAMP 20, or proadrenomedullin N-terminal 20 peptide, is liberated from proadrenomedullin by proteolytic cleavage and is a potent hypotensive and catecholamine release inhibitory peptide. PAMP 20 (human) displays potent antimicrobial activity against standard bacterial strains, with a mechanism of action not involving the microbial cell membrane but instead targeting binding to bacterial DNA.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          Proadrenomedullin N-terminal 20 peptide, PAMP (1-20)
          Molecular Formula
          C112H178N36O27
          Molecular Weight
          2460.87
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 1 mg/ml in water
          Other Properties
          Sequence: H-Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2,ARLDVASEFRKKWNKWALSR-NH2
          Modification: C-terminal amide
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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