Name: PACAP (6-38)
Price: Inquiry

- Overview
  - PAC1 receptor antagonist.
    PACAP (6-38) is a potent and competitive pituitary adenylate cyclase-activating polypeptide receptor (PAC)1 antagonist with an IC50 of 2 nM. PACAP(6-38)] is a potent mast cell degranulator and has an agonistic effect on MrgB3-receptors expressed in oocytes. PACAP (6-38) acts as a functional Cocaine- and amphetamine-regulated transcript peptides (CARTp) antagonist in vivo and blocks its effects on feeding and short-term weight gain.
    
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- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    PACAP 6-38, Pituitary adenylate cyclase activating polypeptide (6-38)
    
    Molecular Formula
    
    C182H300N56O45S
    
    Molecular Weight
    
    4024.8
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble to 2 mg/ml in water
    
    Other Properties
    
    Sequence: H-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-OH,FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
    Modification: C terminal amide
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

PACAP (6-38)

PACAP (6-38)

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