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Overview
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P5091 is a cell permeable, selective and potent inhibitor of ubiquitin-specific protease 7 (USP7, IC₅₀ = 4.2 µM) and USP47. P5091(P005091) induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. It inhibits tumor growth in animal models of cancer.
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Overview