OP-145

- Overview
  - OP-145 is a synthetic antimicrobial peptide (AMP) similar to the human cathelicidin LL-37. OP-145 consists of 24 amino acids and has demonstrated antibacterial and cytotoxic properties.
    
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    Background
    
    OP-145 interacts with phospholipids in bacterial and mammalian cell membranes leading to membrane thinning and permeabilization.
- Properties
  - CAS Number
    
    Not Established
    
    Molecular Formula
    
    C142H246N46O31
    
    Molecular Weight
    
    3093.762
    
    Appearance
    
    Off white to light yellow powder
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: OP-145 is active against Staphylococcus aureus at 0.8-1.6 µM and may be effective against other Gram-positive bacteria.