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Overview
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Nicotinamide (Vitamin B3), USP is water-soluble amide form of Nicotinic acid. It is a poly (ADP-ribose) polymerase (PARP) inhibitor, involved in regulation of many cellular processes. It was discovered between 1935 and 1937. Commercially, Nicotonamide is made from nicotinic acid or nicotinonitrile. Structurally, it consists of a pyridine ring to which a primary amide group is attached in the meta position. It shows promise in cell therapy research for diabetes, since it can induce embryonic stem cells into insulin-secreting cells.
Nicotinamide (Vitamin B3), USP conforms to United States Pharmacopeia specifications.Please contact us at for specific academic pricing.
Background
In cells, Nicotinamide is the precursor to Nicotinamide Adenine Dinucleotide(NAD), an essential coenzyme in ATP production and substrate for Poly-ADP-Ribose Polymerase-1 (PARP-1). It is also a precursor to Nicotinamide Adenine Dinucleotide Phosphate ( NADP), both of which are involved in redox reactions. PARP inhibitors are involved in many cellular processes such as DNA repair, cell cycle progression, and cell death.
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Overview
Nicotinamide (Vitamin B3), USP
Nicotinamide (Vitamin B3), USP
Catalog Number:
CR04341407TOK
Mfr. No.:
TOK-N018
Price:
$141
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