Name: N-Acetyl-D-galactosamine
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- Overview
  - N-acetyl D-galactosamine (GalNAc) is an aldohexose (2-Acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-Acetyl group (Collins, 2006). N-acetyl D-galactosamine forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of GalNAc residues attached to the IgA O-linked glycans of Crohns Disease patients was significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohns Disease (Inoue, 2012).
    
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- Properties
  - Alternative Name
    
    GalNAc;2-Acetamino-2-deoxy-a-D-galactopyranose;N-Acetylchondrosamine
    
    CAS Number
    
    1811-31-0
    
    Molecular Formula
    
    C8H15NO6
    
    Molecular Weight
    
    221.21 g/mol
    
    MDL Number
    
    MFCD00065372
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Collins (2006) Dictionary of Carbohydrates, Chapman&Hall, A206,
    Inoue et al (2012), Deficiency of N-acetylgalactosamine in O-linked Oligosaccharides of IgA Is a Novel Biologic Marker for Crohns Disease, Inflammatory Bowel Diseases, 18(9),