Methyl a-D-mannopyranoside - Amerigo Scientific

- Overview
  - Methyl α-D-mannopyranoside is a methylated sugar used as an inhibitor of lectin-conjugate binding (Derewenda, 1989). It is commonly used in protein purification for eluting glycoproteins and other glycoconjugates from affinity chromatography columns of agarose lectin (Takahashi, 1974). In addition, Methyl α-D-mannopyranoside can be used in the mannosylation of lipid nanoparticles (LNPs) for vaccine or drug delivery which targets Antigen Presenting Cells (APCs) through mannose receptors (Maretti, 2017). Methyl α-D-mannopyranoside is also known as Methyl alpha-D-mannoside or alpha-Methyl-D-mannoside.
    
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- Properties
  - CAS Number
    
    617-04-9
    
    Molecular Formula
    
    C7H14O6
    
    Molecular Weight
    
    194.18 g/mol
    
    MDL Number
    
    MFCD00063262
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - Derewenda et al (1989). The structure of the saccharide‐binding site of concanavalin A. The European Molecular Biology Organisation Journal 8:2189-2193.
    Takahashi et al (1974). Purification of gamma-glutamyltransferase of rat kidney by affinity chromatography using concanavalin A conjugated with sepharose 4B. Biochimica et biophysica acta 371(1):71-75.
    Maretti et al (2017). Surface engineering of Solid Lipid Nanoparticle assemblies by methyl α-d-mannopyranoside for the active targeting to macrophages in anti-tuberculosis inhalation therapy. International journal of pharmaceutics 528(1-2):440-451.

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